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PE134000: α-GalNAc-PEG3-Azide label-new Abnormal Akt signaling in bladder

SKU: 11900794609

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USD225.00 USD262.00

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Description

Abnormal Akt signaling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells

Tumour-associated carbohydrate antigen (TACA)

α-D-GalNAc-Ser-NH-Biotin

33 / A β-D-glucose ligand equipped with an azide handle through a hydrophilic PEG3 spacer

enzymatic cleavage releases 4-nitrophenol

PE134000: α-GalNAc-PEG3-Azide label-new Abnormal Akt signaling in bladderC14H26N4O8 378. 38 An D N acetylgalactosamine (GalNAc) ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the

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