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10.1016/j.burns.2004.10.013 15 BraddockM.CampbellC

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Studies, predominantly in animal models, have explored its effects on wound healing, tendon and ligament repair, gut health, and neuroprotection

Furthermore, Clic4 could be involved in mt-membrane potential generation in mtDNA-depleted cells, a feature required to prevent apoptosis and to drive continuous protein import into mt [41]

41 Additionally, SRT1720 activates the AMPK pathway and improves IRS-1/Akt signaling, contributing to enhanced insulin sensitivity