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[DOI] [PMC free article] [PubMed] [Google Scholar] 128.Han J.-H., Park J., Kang T.-B., Lee K.-H

Chemical sunscreens don't offer the same protection for melasma, and in some instances, they may even trigger allergic reactions that can make melasma worse, she says

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As such, it is not a surprise that many of the therapies proposed to target NSC loss of function and depletion may provide their beneficial effects through enhancing mitochondrial functionality to prevent excessive oxidative stress, including NAD + supplementation, metformin-induced mitochondrial biogenesis, and antioxidant supplementation (Khacho et al., 2019)