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NF-B pathway inhibition: Nuclear factor kappa B (NF-B) is master transcription factor regulating inflammatory gene expression

This mechanism dramatically increases phosphorylation of focal adhesion kinase and paxillin proteins without changing total protein amounts[6]

Astragalus polysaccharide (APS) can prevent experimental colitis in mice and ferroptosis in human Caco-2 cells by inhibiting this signaling pathway [155], suggesting that ferroptosis may be regulated by the Nrf2/HO-1 signaling pathway in DSS-induced UC

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Huperzine A: is it an effective disease-modifying drug for Alzheimer's disease