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Weight loss of -6.8%, -8.1%, and -10.0% were seen at 5.0 mg, 7.4 mg, and 10.0 mg doses, compared to -5.8% with liraglutide 3.0 mg

To investigate the possible mechanism of PanIN progression in humans, Gier et al

Post-hoc analyses of phase IIIII, controlled trials suggest a possible cardioprotective effect with a trend for a lower incidence of major cardiovascular events with gliptins than with placebo or active agents

A maintenance dose may be lower than the dose used during active weight loss, but it can also be the same dose or even a relatively high one

Initiation rates for AOM GLP-1 RA are about the same in June 2025, relative to March 2025 (-1.3%)