Acts as a functional catalyst to increase basal metabolic rate through the activation of glucagon receptors
Many patients start therapy motivated, but early side effects can quickly discourage continued use
Reduces appetite and increases satiety to support sustainable weight management Enhances insulin sensitivity and reduces post-meal glucose spikes to help maintain healthy glucose levels Acts on brain pathways that control hunger and food intake Improved weight and metabolic control may help reduce risk factors associated with cardiometabolic disease Semaglutide is a GLP-1 receptor agonist that mimics a natural hormone involved in regulating appetite, insulin secretion, and blood sugar levels
Other common side effects include: Fatigue, headache, and dizziness Disturbances of the digestive system, such as heartburn, nausea, vomiting, and bloating Diarrhea or constipation Stomach pain On rare occasions, semaglutide injections can cause severe side effects, including allergic reactions
Extracellular calcium and cAMP: second messengers as third messengers