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the dysfunctioning of the mitochondria fails to control the ROS species via some major targets/genes such as SIRT3, FOXO, and PPARGC1A, thus, enhancing the activity of the mitochondria and these genes could/maybe the option to counter the ROS level and oxidative stress to prevent the neuronal death 31

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Glutathione is made in every cell in the body, but after our twenties our ability to produce it starts to decline by 8-10% every decade as part of the natural ageing process