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This view motivated attempts to confer stress resistance in plants by overexpression of antioxidative enzymes (eg, Foyer et al

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Notably, finerenone significantly reduced albuminuria, achieving a 30% reduction in UACR at 6 months compared to placebo (least-squares mean ratio 0.70

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Additionally, they preserve mitochondrial integrity and suppress ROS-induced AMPK-FoxO3 and glucocorticoid pathways, while enhancing antioxidant responses and HSP70 expression