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This unique delivery system is designed to enhance the absorption of glutathione through the oral mucosa, directly entering the systemic circulation

Additionally, PCs alleviated DN pathology, such as glomerular basement membrane thickening and central dilatation, by modulating mimecan protein expression through the NF-B p65 pathway (Zhou et al., 2016) (Figure 8)

Lungs remarkably contain the highest relative level of GLP-1 receptors in the body [86], and GLP-1 appears in much higher concentrations within bronchoalveolar fluid compared with serum, which may indicate a specific function in the lungs [87]

This is illustrated in the figure at right

Oral mucosal lesions are typically detected a decade later than labial lesions