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Anyone with metabolic, cardiac, GI, hepatic, or renal disease or who is pregnant, breastfeeding, or planning pregnancy should not consider it without licensed clinical care

Niacinamide (Vitamin B3): A high-purity skin-perfecting agent that improves light reflection on the skins surface by refining texture and strengthening the defensive moisture barrier

The compound was first characterized in detail in a landmark 1998 publication by Raun et al

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Individual absorption rates vary significantly based on gastric pH, intestinal permeability, and concurrent medications