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Both examples are characterised by contextual conditions that are so the assumption rather hostile to sustainability transformation: Structural weakness, shrinking dynamics, brain drain and capacity reduction in the past, negative transformation experiences in the course of deindustrialisation and socio-political upheavals
Thus, cytosolic HSP70 may affect proteostasis in the ER in the absence of active GRP78 isoforms, although the distinct mechanisms involved remain to be elucidated
Chapter 2 - chemistry of reactive species
A subset of dedifferentiated -cells were at early stage to convert into -cell in LOsG-treated animals As a subset of FoxO1-deficient -cells adapts the -cell fate, resulting in hyperglucagonemia 22 , we determined pancreatic glucagon mRNA in LOsG-treated -cells, which were associated with low or absent FoxO1 expression