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FDA engagement planned via an End-of-Phase 2 meeting in Q1 2026

The mean age of the study patients was found to be 32.90 7.92 years which was similar to the studies by Kumar et al .,[] Garg et al .,[] and Achar and Rathi.[] The disease duration of melasma in majority of patients (56.0%) was between 1 to 3 years, which is in concordance with the study by Kumar et al .[] Similar to the study by Khurana et al ., majority of patients (78%) in our study were found to be of Fitzpatrick skin type IV, followed by Fitzpatrick skin type V and type III.[] The assessment of mean difference in VAS over both cheeks before and after TA (right cheek) and glutathione (left cheek) revealed that both the treatment options were effective [Table 2]

Peptide therapy works by using compounded prescription peptides to modulate a specific physiological pathway

In contrast, Orlistat produces modest results of 4-8% weight reduction

Zepbound is specifically FDA approved for weight loss in adults with a BMI of 30 or higher