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XIGDUO XR is contraindicated in patients with an eGFR below 30 mL/min/1.73 m and end-stage renal disease due to the metformin HCl component [see CONTRAINDICATIONS , WARNINGS AND PRECAUTIONS , and Use In Specific Populations ]

A Quick Look at the Mechanism GLP-1 receptor agonists can help lower blood sugar and promote weight loss by mimicking a natural hormone that tells your body to release insulin, slow digestion, and reduce appetite

Individual responses vary considerably based on baseline weight, rate of weight loss, underlying conditions such as PCOS, and overall metabolic health

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