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While this trial showed trends toward fat loss in the treatment groups, the primary endpoint of statistically significant weight reduction compared to placebo was not consistently achieved across all dose groups, and effect sizes were more modest than hoped

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Biol Psychol 87:183194 Tangvarasittichai S, Pongthaisong S, Tangvarasittichai O (2016) Tumor necrosis factor-, interleukin-6, C-reactive protein levels and insulin resistance associated with type 2 diabetes in abdominal obesity women