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While these findings are promising, research is still evolving
Nrf2, which is usually bound to Keap1 by ubiquitination or degraded by Keap1 in the absence of oxidative stress, is translocated to the nucleus when oxidative stress modifies the conformational structure of Keap1 and prevents it from binding Nrf2 (Komaravelli and Casola, 2014
Cell 175 , 16341650 (2018)
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Petersburg Institute of Bioregulation and Gerontology studied Epithalon across several decades, publishing findings in journals including Annals of the New York Academy of Sciences and Neuro Endocrinology Letters
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