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They are required to register with the FDA and are subject to more stringent requirements and oversight than traditional compounding pharmacies

Recommendations Given these factors, we do not recommend expanding coverage to include compounded GLP-1 agonists

Classically hepatocyte hypertrophy occurs without increase in hepatocyte numbers or DNA (i.e., hyperplasia or polyploidy), however, combinations with increased mitoses do occur (e.g., PPAR-alpha agonists)

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