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Furthermore, in Calcr Cre rats injected with adeno-associated virus (AAV)-DIO-hM3Dq-mCherry in the AP, essentially all mCherry-identified AP Calcr Cre neurons contained CALCR but not GLP1R immunoreactivity (we lack a reliable reporter allele for Calcr Cre in rats

Habig WH, Pabst MJ, Fleischner G, Gatmaitan Z, Arias IM, Jakoby WB

Additional experimental models incorporating glucose tolerance testing and fasting biomarker analysis show no significant changes in plasma glucose or insulin levels following exposure to AOD 9604

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Some particularly stable peptides retain activity for even longer periods