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Identification and characterization of trimethylamine-N-oxide uptake and efflux transporters

PubMed Central , PLoS ONE , vol

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Nat Rev Cardiol 20(7):475494 Yuen MMA (2023) Health complications of obesity: 224 obesity-associated comorbidities from a mechanistic perspective

Preliminary clinical investigations reveal that the GLP-1 receptor agonist semaglutide accelerates diabetic foot ulcer closure independently of glycaemic improvement, implying that incretin-based therapies may modulate inflammatory resolution, angiogenesis, and extracellular-matrix remodelingthereby extending the therapeutic footprint of antidiabetic agents into the realm of tissue repair (131)