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Semin Arthritis Rheum (2018) 48:5537

These peptides have received considerable attention in sports drug testing and are listed on the World Anti-Doping Agency (WADA) Prohibited List due to their ability to induce secretion of endogenous growth hormone (GH)

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Gut microorganisms may affect the central nervous system through this interaction, whereas the neurological system governs the generation and secretion of gut hormones

[50] [51] [52] The FDA approved tirzepatide based on evidence from nine clinical trials of 7,769 participants with type 2 diabetes, of whom 5,415 received tirzepatide