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It appears to interact with key biological systems, such as the nitric oxide pathway and antioxidant defenses, which may explain its broad therapeutic effects

WHAT THIS STUDY ADDS The present post hoc analyses demonstrated that 72-week treatment with tirzepatide was associated with consistent reductions in blood pressure, shifting the blood pressure distribution curve to the left, frequently leading to normalisation of blood pressure values in participants with elevated blood pressure and stage 1 and stage 2 hypertension at baseline, with relatively few blood pressure-related adverse events

The role and regulation of the peroxisome proliferator activated receptor alpha in human liver

Park E, Chung SW

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