Understanding the Long-Term Impact of GLP-1 Meds on Digestive Health GLP-1 agonists have long served as medication for Type II diabetes, but in the last few years they have gained increasing popularity as an effective weight loss agent
Glucose metabolism Many NRF2-regulated detoxification pathways rely on a supply of glucose for their activity
In addition, the oxidants may also originate from cytosolic enzyme systems, e.g., NADPH oxidases, and from exogenous triggers such as ionizing radiation and chemotherapeutics
Moreover, several studies have related CCKs metabolic and therapeutically relevant biological activities to those of the incretin hormones GIP (gastric inhibitory polypeptide) and GLP-1, as well as amylin and leptin
Patients with a history of gastrointestinal conditions such as acid reflux, irritable bowel syndrome, or gastroparesis should be especially cautious when starting GLP-1 medications