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Once in the body, creatine is primarily taken up by muscle tissue, with approximately 1-2% per day non-enzymatically converting to creatinine, which is then excreted by the kidneys

This helps you understand how often, how hard, how long, and what type of activity to perform

Theres a black box warning against use in people with personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2

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However, some patients may experience increased thirst due to related factors such as hyperglycaemia, dehydration from gastrointestinal side effects, or inadequate fluid intake