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6a, b) Delaying G6PDi-1 treatment for 1 h post-stimulation allowed for substantial cytokine production, indicating that G6PD and the PPP likely play an important role in the early signaling events following stimulation

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These products are designed to influence pigmentation

In particular, glutathione (GSH) depletion is a common feature of apoptotic cell death triggered by a wide variety of stimuli including activation of death receptors, stress, environmental agents, and cytotoxic drugs

For these reasons, the applicant believes that the Axoguard HA+ Nerve Protector TM meets the device category criterion