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If an injectable compounded product is used after the BUD, there are two major concerns: The concentration of the active ingredient may be less than labeled

Epigallocatechin gallate (EGCG) originating from green tea has been studied in mouse and cell models, and it has been found that it is effective as a ROS scavenging agent, mitochondrial apoptosis protector, mitochondrial bioenergetics activator, and respiratory chain promotor [98, 99]

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For psoriasis (HR 1.19), an unmeasured confounder would require risk-ratio associations of at least 1.67 with both GLP-1 RA initiation (vs DPP-4i) and incident psoriasis to fully explain the observed effect