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rhIGF1 in IDDM Study Group

In 2022, first-line LTP treatments (Lanadelumab and berotralstat) and GLP-1 receptor agonists were not reimbursed in Croatia and only became available in 2024

10.1016/j.mtbio.2025.102053 176

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One of the most informative human studies in this field is one pilot trial, which demonstrated that patients achieving robust glycemic improvements following GLP-1 RA therapy displayed a distinct baseline microbial profile characterized by greater -diversity and enrichment of SCFAproducing bacteria, including Roseburia inulinivorans , Lachnoclostridium spp., Butyricicoccus , and Faecalibacterium prausnitzii (40)