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While these effects are not evidence of addiction, they do indicate that the brain and nervous system can adapt to long-term SSRI use

Along with obesity-related conditions like heart disease, stroke and some cancers, mental health disorders are significantly correlated with body weight: 43 percent of adults with depression were obese, and studies point to a complex bidirectional relationship, in which obesity increases risk of depression and depression increases risk of obesity

In some studies, these medications enabled: Faster achievement of technical operability Easier laparoscopic access Improved metabolic control Higher diabetes remission rates, especially in insulin-dependent patients 2

PMID 2781235

Chen et al., 2024)