Intracellular glutathione peroxidase 4 (GPX4) uses reduced glutathione (GSH), an antioxidant, to reduce lipid peroxides generated by reactive oxygen species (ROS).* However, when lipid peroxides accumulate due to GPX4 disruption or GSH depletion, ferroptosis is triggered
Then, they were placed in 15% sucrose (Sigma-Aldrich, #S9378) for 6 h and in 30% sucrose overnight at 4 C using a tube rotator
In an upcoming issue, Part 2 will conclude with methods of detection and strategies for validation of stability-indicating methods
Vitamin B-12 is essential for producing red blood cells, maintaining neurological function, and supporting DNA creation
This scan is used to confirm an unclear diagnosis of acute cholecystitis (Tanaja 2018)