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However, several cases have been reported, including the case of a woman with type 2 diabetes, hypertension, hyperlipidemia, and depression [48]

Saliu JA, Oboh G, Omojokun OS, Rocha JB, Schetinger MR, Guterries J, et al

Clinical trial data from Retatrutide research and from comparable GLP-1 compound trials consistently shows that participants maintaining 80g+ of protein daily preserved lean mass significantly better than those whose protein intake dropped under caloric suppression

People with liver disease, heavy alcohol intake, heart failure with low oxygen risk, or a history of pancreatitis may need extra caution

Deisseroth, A, Fu SQ, Hanania E, Randhawa G, Claxton D, Reading C, Champlin R, Andreeff M , Logothethis C, Hong WK, Holmes F, Hortobagyi G, Benedict W