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All patients ( n = 209) with MM ( n = 41), NSCLC ( n = 91), urothelial cell carcinoma ( n = 8), renal cell carcinoma ( n = 21), head and neck cancer ( n = 28), gastric cancer ( n = 19) or Hodgkin lymphoma ( n = 1) treated with pembrolizumab or nivolumab between November 2, 2015 and October 31, 2018 at Nagoya University Hospital were included in this study, and observed until death or referral to another hospital

Mostly administered within hospital settings

Dizziness with blurred vision should never be ignored

This intrinsic oxidative vulnerability of the brain and growing evidence of neurodegenerative changes associated with many psychiatric syndromes suggests that oxidative damage may be a plausible pathogenic candidate

Its anti-inflammatory and antiproliferative properties, similar to those of methotrexate, suggest potential benefits in improving metabolic syndrome characteristics in psoriatic patients (67)