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References 1 GoreACChappellVAFentonSEFlawsJANadalAPrinsGSet al

Other systemic effects (rare): Adults typically clear small amounts of benzyl alcohol without issue

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Additional preclinical work published in Cell Chemical Biology evaluated NNMT inhibition in similar diet-induced obesity models and confirmed the pattern: significant reductions in body weight gain, adipose tissue expansion, and circulating triglycerides compared to untreated controls

Impairment of adipogenesis leads to ectopic fat deposition in skeletal muscles, liver, and kidneys, triggering IR in these tissues and increased risk of T2DM