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Starting body composition plays a major role, with individuals carrying higher body fat percentages often experiencing more dramatic absolute changes, while leaner individuals may see slower but steady improvements in stubborn fat areas

The LEADER trial 28 (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results) studied a 1.8-mg dose in more than 9,000 patients with type 2 diabetes and found the incidence of acute pancreatitis was similar between the liraglutide and placebo groups (0.4% vs 0.5%, respectively)

Preliminary results have been encouraging, but long-term success remains unknown

Black coffee or tea without additives is acceptable

PMID 25283155