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More chronic, placebo-controlled human studies are required to evaluate not only the bioavailability and efficacy of various polyphenol formulations and delivery systems but also to establish standardized dosages, monitor potential side effects, and assess inter-individual differences in responses due to genetics and gut microbiota composition (126, 127)

Gynecol Endocrinol

It frequently results in developing pimples or zits on the skins surface, leading to redness, swelling, discomfort, and heat [331]

doi: 10.1016/j.neuroscience.2016.03.056 68 SotoMCaiWKonishiMKahnCR

To account for within-patient clustering, a MANCOVA including patient as a fixed effect was conducted as a robustness check