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Drugs such as DFOM and deferiprone can chelate iron and thereby inhibit ferroptosis
It has been estimated that 33% of the population have an issue with these genes making them more susceptible or prone to further oxidative stress and potential degenerative disease
Among the stilbene-based polyphenolic chemicals, RES has shown more pharmacological effects in recent years, and there are other chemicals in the same class of PA that need to be further investigated for their pharmacological effects in DKD
It is also almost entirely preclinical
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