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M1 macrophages amplify inflammation, eliminate pathogens, and inflict tissue damage by secreting a repertoire of proinflammatory mediators, whereas M2 macrophages are involved mainly in tissue repair (fibrosis and neovascularization) (186)
And people have gradually realized the importance of immune cells in TME in anti-tumor therapy with the discovery of immune checkpoints and their significant efficacy in anti-tumor therapy (3), the immune cells in TME mainly include tumor-associated macrophages (TAMs), natural killer (NK) cells, dendritic cells (DCs), tumor-associated neutrophils (TANs), myeloid-derived suppressor cells (MDSCs) and T cells (4)
By supporting collagen formation, tissue strength, and cellular repair, SynaPep BPC-157 helps restore function and comfort