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Saturation mutagenesis at seven key extracellular domain sites identified positions whose substitution selectively decoupled these two signaling axes, with computational analysis of the resulting sequence-function data revealing correlations between extracellular domain residue chemistry and downstream signaling outcome (Xie et al., 2025)

[11] Breast milk functions like a carefully regulated recipe: The foundation remains consistent, but higher-quality inputs refine the final result

2020;43(Suppl 1):S13551

In addition, the amount of L-carnitine in tissues is conditioned by factors other than diet availability and endogenous synthesis

More replicates were performed for the study, but due to laser damage/change and microscope/camera re-alignment issues, they were dismissed from the study for consistency