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Formononetin treatment dose-dependently reduced mast cell degranulation, histamine release, and inflammatory cytokine expression in RBL-2H3 cells and mouse bone marrow derived mast cells, reducing IgE-induced MAPK and NF-B expression in vitro [122]

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TMX also increased the expression of caspase-3 and glial fibrillary acidic protein

Hair thinning typically appears 3-6 months after starting treatment, which aligns with the normal hair growth cycle

Synthesis, antioxidant and anti-inflammatory properties of an apocynin- derived dihydrocoumarin