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Despite its widespread prevalence, NAFLD is frequently underdiagnosed and undertreated, making early intervention essential for preventing long-term complications

For example, platinum (IV) prodrugs activated by intracellular GSH have demonstrated enhanced tumor selectivity and reduced systemic toxicity in clinical trials

Candidate drugs are in development for treatment of sarcopenic obesity, often a disease of aging and defined by the coexistence of obesity and sarcopenia 68

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