Semaglutide (2.4 mg) significantly reduces hepatic steatosis and ALT and was studied in NASH resolution trials (e.g., ESSENCE) [34]
A search on clinicaltrials.gov for relevant unpublished trials revealed that NCT00086684, sponsored by Johnson & Johnson, was terminated early for lack of efficacy
Still, outcomes can vary depending on dose, duration, baseline weight, health status, lifestyle factors, and individual biology
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