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Patients should be under regular clinical review to monitor efficacy, tolerability, and cardiovascular risk factors

Biologics will face slower erosion than small molecules, but the formulary contracting dynamics, not just the legal patent status, will determine the actual revenue trajectory

For patients in particularly hot climates (such as Arizona, Texas, or Florida), consider using pharmacies that specialize in temperature-sensitive biologics and have robust cold-chain logistics

Its clinical development was halted, so there is no completed pivotal trial, no approved label, no reviewed dose, and no regulatory safety determination