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Figure 2 The pro-inflammatory and anti-inflammatory activities of Kupffer cells (KCs) depend on their polarisation and include the promotion of TNF- and IL-10 secretion

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A separate 2013 review in the peer-reviewed journal Alcoholism: Clinical and Experimental Research synthesizing how alcohol consistently reduces slow-wave sleep duration and disrupts the nighttime endocrine pulse pattern reaches the same conclusion across multiple study populations

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If you do drink, go slowly and expect a stronger response than usual

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