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Interestingly, succinate supplementation also phenocopied decreased KG in its ability to inhibit proliferation of CCNE1-driven cells in the presence of DNA damaging agents and was rescued by KG supplementation ( Fig

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the patient has an initial appointment during which a tendon biopsy is collected from a healthy tendon and sent to Ortho Cell for processing, and then later the patient returns for an injection of the tenocyte cells isolated and grown from the biopsy