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Regular laboratory monitoringincluding lipid panels, liver function tests, and A1Chelps ensure the combination remains safe and effective over time

These include for example arterial plasma concentration as an input signal for compartmental or graphical modeling of radioligand/target receptor interactions such as Binding Potential (BP), a well understood and validated vascular contribution to the PET signal in tissue as well as the possibility of using brain regions without receptor expression as reference tissue