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The global prevalence of diabetes continues to rise, with projections indicating a substantial increase in disease burden over the coming decades ( Patients with T2DM and ESRD represent a particularly high-risk population characterized by advanced metabolic dysfunction, a high burden of cardiovascular disease, and extensive polypharmacy ( Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) improve glycemic control by increasing glucose-dependent insulin secretion, suppressing glucagon release, delaying gastric emptying, and inducing weight loss

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Ma, H., Ding, Z., Xie, Y., Li, L., Li, D., Lou, K., Wang, W., & Xu, H

These outcomes also depend "heavily" on patient characteristics, the expert added

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