Though a slower rate of weight loss, body fat is the specific type of weight we are looking to shift long-term
Preclinical and clinical studies suggest that GLP-1RAs may reduce EAT volume/thickness, potentially exceeding overall weight loss, attenuate EAT inflammation and fibrosis, improve cardiomyocyte calcium handling, mitigate oxidative stress, and suppress pulmonary vein ectopy, thereby potentially reducing AF susceptibility and recurrence post-ablation
Additionally, there are serious safety warnings regarding the risk of birth defects, so women of childbearing age must use effective contraception
Ro's model assumes patients can afford brand-name medications or have insurance that covers them
Use barrier protection while on GLP-1 agonists People who have previously experienced infertility may have higher chances of getting pregnant, or getting a partner pregnant, while on GLP-1 agonists