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Diabetes Care, 42 (9), 17241732

It's right there in the fine print of clinical trials

The trial used an intention-to-treat principle, including all participants who underwent randomization, regardless of their adherence or changes in medication

From Retatrutide: Nausea, vomiting, diarrhea, constipation, gastroparesis, and in rare cases, pancreatitis

A notable safety signal is dysaesthesia, which refers to tingling, numbness, or altered skin sensations, reported in about 1 in 5 participants at the 12 mg dose