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LC 50 for K1 cells was ~ 0.4 M, whereas RSL3 treatment did not significantly affect TPC-1 cell viability, suggesting RSL3 selectively inhibits RAS/BRAF -mutant cell lines, such as K1, MDA-T32, and MDA-T68 (Fig

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But angiogenesis also feeds tumors

2020;7:154 Hauschild A, Ascierto PA, Schadendorf D, Grob JJ, Ribas A, Kiecker F, Dutriaux C, Demidov LV, Lebb C, Rutkowski P, Blank CU, Gutzmer R, Millward M, Kefford R, Haas T, DAmelio A Jr, Gasal E, Mookerjee B, Chapman PB