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Presentations at the most recent ADA scientific sessions in 2024 included discussions of clear benefits to reduce liver fat in MASH (formerly called NAFLD) with tirzepatide (Loomba, NEJM, 2024) and a phase 2 trial with the triagonist (GLP-1/GIP/Glucagon), retatrutide (Sanyal, Nature Medicine, 2024)

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Recognizing this, our analysis suggests that GLP-1 use with strong adherence is linked with improved employee health outcomes and a slower rise in medical costs over time, even as treatment costs continue to shift

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