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This was done by redesigning our original PepD construct to have a weaker expression using a Bba_I1051 promoter instead of a Bba_J23100 promoter

A more gradual rise in blood levels could reduce the sharp peak that triggers GI side effects in sensitive individuals

Animal studies on BPC-157 have demonstrated a favorable safety profile, with no established LD50 (lethal dose) and no documented organ toxicity, carcinogenicity, or mutagenicity at tested doses

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BPC-157 has also demonstrated promise in supporting gut health by protecting the stomach and intestinal lining, and is studied for its roles in cytoprotection, vascular integrity, and tissue repair pathways