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Corke, MJ

These observations conclusively demonstrate that PDA@Pt can restore the mitochondrial membrane potential compromised by LPS, and the NIR light alone also has a certain regulatory effect

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Moreover, Erastin can increase intracellular iron availability by upregulating heme oxygenase, which releases iron by degrading heme ( Despite the inherent resistance of EMS tissue to ferroptosis, studies have shown that Erastin can still effectively induce ferroptosis in EMS lesions, leading to tissue atrophy and cell death