And does size really matter
Hierarchical clustering of commonly engaged proteins by the fold increase in target engagement in senescent versus non-senescent conditions (referred to as senescence selectivity) identified broadly highly-reactive proteins, clusters of proteins with specificity to certain chemotypes and others (such as GPX4) that were enriched in probes related to three different SCLAs (Fig
They are proteins of non-enzymatic type, present in the venoms of many snakes, which may have a vast range of effects on the human body: as it has as target also various types of ion channels, they can have neurotoxic effects and it is not excluded that this can be also the case of the venom of Boiga dendrophila
GLP-1s can influence all three
Keys, A.J., Wiener, D.J., Pacini, S.M., Sun, C.Z., Sandusky, L.E., Zhong, H.Y